Sam Rockwell Wolf (voice) Marc Maron Snake (voice) Awkwafina Tarantula (voice) Craig Robinson Shark (voice) Anthony Ramos Piranha (voice) Zazie Beetz Diane Foxington (voice) Danielle Brooks Kitty Kat (voice) Natasha Lyonne Doom aka Susan (voice) Marija Bakalowa Pigtail Petrova (voice) Alex Borstein Commissioner Misty Luggins (voice) Richard Ayoade Professor Marmalade (voice) Lilly Singh Tiffany Fluffit (voice) Omid Djalili Mr. Soliman (voice) Colin Jost Mr. Moon (voice) Jaime Camil Handsome Jorge Garcia (voice) Michael Godere Bank Manager (voice) Jorge R. Gutierrez Lucha Spectator (voice) Joey Naber Servant / Cairo Cop 1 (voice) Ashley Lambert Deputy / Computer Voice (voice)